Course Catalog

Ecological Risks of Chemicals

Many chemists, biologists, product safety and regulatory personnel are engaged in the testing of new & existing chemical products, their hazard classifications for labeling, product registrations, and ecological risk assessments. The first step in these processes is to understand the rationales for developing data pertaining to the behaviour and impacts of chemicals in the environment. This is followed by appreciation of the methodologies for developing plus interpreting these test data applicable to ecological assessments, and finally, use of these data in development of product literature, MSDSs, and safety guidelines. Each module will provide understanding of various parameters central to achieving evaluation and communication of potential impacts of chemicals on the environment.

Course Details

Key Topics

  • The persistence of chemicals in the environment
  • Bioaccumulation
  • Assessment of the adverse effects on biological species imparted by chemicals
  • Ecological risk assessment

Information

Many chemists, biologists, product safety and regulatory personnel are engaged in the testing of new & existing chemical products, their hazard classifications for labeling, product registrations, and ecological risk assessments. The first step in these processes is to understand the rationales for developing data pertaining to the behaviour and impacts of chemicals in the environment. This is followed by appreciation of the methodologies for developing plus interpreting these test data applicable to ecological assessments, and finally, use of these data in development of product literature, MSDSs, and safety guidelines. Each module will provide understanding of various parameters central to achieving evaluation and communication of potential impacts of chemicals on the environment.

Who Should Attend

Any scientist engaged or interested in engaged in the testing of new & existing chemical products, their hazard classifications for labeling, product registrations, and ecological risk assessments.

Benefits

These modules will provide understanding of various parameters central to achieving evaluation and communication of potential impacts of chemicals on the environment.

Agenda

Each lecture will include brief discussion of the entire field of ecological risks, and how the specific topic fits into the broader picture. Each session will address an array of chemical classes (e.g., pesticides, pharmaceuticals, solvents), and provide case histories to illustrate principles discussed.

Module 1: PERSISTENCE

The persistence of chemicals in the environment is a key factor that generates concerns regarding their presence in ecological media. Persistence confers the potential for wide-spread environmental distribution as well as long-term residence in air, water, and soil. Prolonged residence in these media can lead to increased induction of adverse effects in humans, and domestic and wildlife species. This course will describe various means, experimental and QSAR modeling, for assessing the ecological longevity of chemical substances. Topics:

  • Chemical properties key to assessment of persistence
  • Non-biological pathways
  • Biological endpoints and tests
  • Computer modeling of environmental degradation
  • Regulatory criteria
  • Case histories


Module 2 – BIOACCUMULATION

Bioaccumulation is the uptake of chemicals into biological species from surrounding media and food sources. This transmembrane passage of substances is necessary for eliciting toxic effects in chemically-exposed species as well as the biomagnification of chemicals in food chains. A high level of bioaccumulation is considered undesirable as it is deemed a potential threat to cause as yet unknown deleterious effects on future generations of aquatic and terrestrial species. This course will describe experimental means for assessing bioaccumulation of chemical substances in a variety of biological models. Topics:

  • Chemical properties key to assessment of bioaccumulation
  • Biological endpoints and test methods
  • Computer modeling of environmental bioaccumulation
  • Regulatory criteria
  • Case histories

Module 3 – ECOTOXICITY

Assessment of the adverse effects on biological species imparted by chemicals is an important process in ascertaining ecological risks associated with their manufacture, use, and end-of-life disposal. According to projections of ecological distribution, testing of potential target species provides essential information describing the qualitative and quantitative adverse impacts of substances disseminated in the environment. The course will describe an array of toxic endpoints, and application of these data for classification & labeling purposes.

  • Chemical properties key to assessment of toxicities
  • Biological testing ? aquatic & terrestrial
  • Computer modeling of environmental toxicity
  • Regulatory criteria
  • Case histories

Module 4 – ECOLOGICAL RISK ASSESSMENT

Upon collection of ecological toxicity and fate information, it is necessary to interpret and communicate these characterizations of chemical effects. Many of the processes involve matching test data with regulatorily-prescribed criteria for hazard classifications. Others require in-depth use of various environmental models to ascertain the safety of environmental sectors based upon both toxicity data and potential environmental dissemination of fugitive chemicals. A Persistent/Bioaccumulative/Toxic classification for a chemical derives from ecotox and fate testing results, and these substances are high priority for banning or commercial restrictions. Topics:

  • Important ecological endpoints used in risk assessments
  • Ecological toxicity & fate criteria for classification & labeling purposes
  • Descriptions of computer models for assessing ecological safety
  • PBT substances ? criteria for a damaging classification
  • Case histories

Course Locations

Date

TBA

This course consists of four modules which can be purchased separately. Each module is approximately 90 minutes long.

Register Online Register Via Mail

Venue

The registration fee includes seven days of access to the content, lecture slides (provided in PDF format), and email access to the instructor.

Each person attending must register individually for this course.


Pricing
Standard $199 per module

About the Instructor

  • Dr. Philip Leber

    has 25+ years experience in toxicological and ecological assessments of chemicals in research and industrial organizations. Dr. Leber teaches Ecological Impact of Chemicals and the webcast course Toxicology For Chemists.