Course Catalog

Enzyme Kinetics and Inhibition

  • Provide an understanding of chemical kinetics, catalysis and reaction mechanisms
  • Introduce and develop the current models for enzymatic catalysis
  • Illustrate various catalytic manipulation strategies
  • Provide examples for enzyme catalysis as targets for drug discovery and protein engineering

Course Details

Key Topics

Introduction to Chemical Kinetics

  • Zero, first and second order rate kinetics
  • Molecularity and reaction mechanisms
  • Effect of Catalysts on reaction rates
  • Temperature dependence of reaction rates

Brief overview of protein structure

  • Primary, secondary, tertiary and quaternary structure
  • Tools to determine structure of proteins

Enzyme catalysis

  • Catalytic strategies involving steady and pre-steady state kinetics
  • Plots and parameters for Michaelis- Menten kinetics
  • Effect of local environment in enzymatic catalysis

Enzyme Inhibition Strategies

  • Types of inhibition
  • Enzyme Inhibition and drug discovery
  • Transition state analogs in drug discovery
  • Enzymes as targets for protein engineering

Who Should Attend

This course is intended for bachelor’s and master’s level scientists with a basic biochemistry background seeking to improve their knowledge. It is also good refresher course for those familiar with enzyme kinetics but are interested in learning more about the applications of enzyme kinetics. The course should be informative for researchers who are interested in working across disciplines and are starting to participate in research involving enzymatic applications.


After this course, you will:

  • Understand the role of kinetics in enzymatic reactions
  • Appreciate the role of kinetics in understanding reaction mechanisms
  • Understand the kinetics of enzyme inhibition
  • Appreciate the role of enzymatic catalysis in drug discovery as well as protein engineering
  • Be able to apply the various enzyme kinetics models to biochemical problems


  • Instruction will be interspersed with literature examples to emphasize concepts
  • Hands on Q&A /activities to enhance understanding of concepts
  • Printed list of relevant literature references
  • Open access to instructor for questions and information after course

Course Locations



Check-in opens at 7:30 a.m. on the day of the course.

Course runs from 8:30 a.m. to 5:00 p.m.


The course fee includes a course binder and a continental breakfast each day.

Five for Four! Register five people for one course, one person for five courses, or any combination in between and your fifth registration is free. Note: This discount is only available if you register by fax or mail and mention this discount. May not be combined with any other offer.

  Member Non-Member
Advanced $795 $995
Standard $1,095 $1,295

About the Instructor

  • Bhavani Balasubramanian

    has over 12 years of research experience in the area of biochemistry and molecular biology. Her most recent industry experience was as a manager of Clinical Efficacy at AVON Products Inc.