Course Catalog

Impact of Early Pharmaceutical Profiling and in Vitro ADME on Drug Development

Participants will gain knowledge of a wide range of topics that impact drug discovery and development such as: the importance of drug-like properties such as solubility, lipophilicity, permeability, and stability; in vivo drug barriers such as ADME and the impact on drug toxicity; the relationship between the barriers; integrating properties into discovery.

Course Details

Key Topics

  • Introduction to drug-like properties
  • Barriers to drug exposure
  • Effect of poor properties
  • Pharmaceutical profiling
  • Drug exposure
  • Identification of metabolites

Information

Participants will gain knowledge of a wide range of topics that impact drug discovery and development such as: the importance of drug-like properties such as solubility, lipophilicity, permeability, and stability; in vivo drug barriers such as ADME and the impact on drug toxicity; the relationship between the barriers; integrating properties into discovery.

Who Should Attend

Scientists involved in the design, synthesis and testing of drug candidates in academic and industrial settings.

Benefits

  • Learn the importance of drug-like properties
  • Understand the relationship between drug barriers and drug-like properties
  • Learn how to integrate properties into discovery
  • Assest in selecting compounds to advance in development

Agenda

Discuss Pharma’s efforts at reducing attrition of drug candidates in development

Introduction to drug-like properties

Barriers to drug exposure

Effect of poor properties

Solubility

Permeability

Lipophilicity

Pharmaceutical profiling

How to measure

Impact on Drug Development

Drug Exposure

Absorption

Distribution

Metabolism

Course Locations

Date

TBA

Check-in opens at 7:30 a.m. on the day of the course.

This Half-Day Course runs from 9:00 a.m. to 12:00 p.m.

Register Via Mail

Venue

The course fee includes a course binder and a continental breakfast each day.

Five for Four! Register five people for one course, one person for five courses, or any combination in between and your fifth registration is free. Note: This discount is only available if you register by fax or mail and mention this discount. May not be combined with any other offer.


Pricing
  Member Non-Member
Advanced $395 $495
Standard $595 $695

About the Instructor

  • Magid Abou-Gharbia, Ph.D., FRSC

    is currently the Associate Dean for Research, Professor of Medicinal Chemistry and Director of the Moulder Center for Drug Discovery Research (MCDDR) at the School of Pharmacy, Temple University, Philadelphia, PA.