Course Catalog

Mastering the Art of Writing Reasonable Organic Reaction Mechanisms

This course is aimed at B.S. and M.S. chemists in the pharmaceutical and contract syntheses industries looking to improve upon their ability to draw a reasonable mechanism for any complex organic transformation.

Registrants will need to purchase a copy of The Art of Writing Reasonable Organic Reaction Mechanisms , 2nd edition, in addition to their registration.

Before the course starts, you should read sections 1.1 to 1.3 and work the corresponding problems at the end of Chapter 1 before arriving to the course. Bring the text to the course.

Course Details

Key Topics

  • How to identify what major class of mechanism is operative.
  • How to get started at drawing a mechanism.
  • When to draw proton-transfer steps under basic and acidic conditions.
  • The fundamental reactions of carbocations.
  • The fundamental organometallic reactions.
  • The fundamental pericyclic reactions.
  • The major mechanisms for substitution at C(sp3) and C(sp2) under various conditions.
  • The mechanisms of typical pericyclic heterocycle-forming reactions.

Information

This course is aimed at B.S. and M.S. chemists in the pharmaceutical and contract syntheses industries looking to improve upon their ability to draw a reasonable mechanism for any complex organic transformation.

Registrants will need to purchase a copy of The Art of Writing Reasonable Organic Reaction Mechanisms , 2nd edition, in addition to their registration.

Before the course starts, you should read sections 1.1 to 1.3 and work the corresponding problems at the end of Chapter 1 before arriving to the course. Bring the text to the course.

Who Should Attend

The course is aimed at B.S. and M.S. chemists in the pharmaceutical and contract synthesis industries. An ability to discern what mechanism is likely to be operating in any particular organic transformation is essential for understanding and remembering new reactions and for identifying why a particular reaction gives an unexpected product instead of the expected one.

Benefits

  • Look at an organic transformation and understand how it is occurring.
  • Be able to formulate mechanistic hypotheses yourself, rather than relying on others to tell you what is happening.
  • Know how to choose appropriate reaction conditions for reactions you are executing.
  • Learn to identify unexpected by-products from a reaction by rationalizing how they might arise.
  • Know how to modify reaction conditions if your reaction doesn’t work as well as you want.

Course Locations

Date

TBA

Check-in opens at 7:30 a.m. on the first day of the course.

Course runs from 8:30 a.m. to 5:00 p.m. each day.

Register Online Register Via Mail

Venue

TBA


Pricing
  Member Non-Member
Advanced $1,495 $1,695
Standard $1,895 $2,095

The course fee includes a course binder and a continental breakfast each day.

Five for Four! Register five people for one course, one person for five courses, or any combination in between and your fifth registration is free. Note: This discount is only available if you register by fax or mail and mention this discount. May not be combined with any other offer.

About the Instructor

  • Robert B. Grossman

    has been a professor in the Department of Chemistry at the University of Kentucky since 1994. He is the author of The Art of Writing Reasonable Organic Reaction Mechanisms.