is Professor and Associate Chair of Chemistry and Biochemistry at Notre Dame; Director of Project Development Team for translational therapeutics research at Notre Dame and other universities in Indiana. He received his B.S. degree in chemistry and mathematics at the University of Minnesota. He then earned his M.S. and Ph.D. degrees in organic chemistry at Cornell University followed by postdoctoral research in synthetic organic chemistry at Harvard University with Nobel Laureate E. J. Corey. Paul has been a university faculty member for 41 years. He held a professorship at another university before coming to Notre Dame in 1984. He is a specialist in synthetic organic chemistry and has over 170 publications and patents in the following areas: development of new synthetic methods; design and development of transition metal reagents and catalysts for selective synthetic reactions, including new enantioselective methods; development of new methods for the total synthesis of natural products synthesis and applications to new pharmaceuticals, including antibacterial and antitumor agents and treatments for rare inherited diseases as part of an international network of collaborators in the U.S.A., Europe, and Asia. This research has led to a therapeutic agent that has progressed to an FDA-approved human clinical trial.
Dr. Helquist has served as Chair of the Chemistry Board of Examiners for the Graduate Records Examination at the Educational Testing Service, as the Director of the National Science Foundation Workshop for College Teachers of Organic Chemistry, and as a consultant to the pharmaceutical industry. Since 1981, he has offered special courses on advanced synthetic organic chemistry on 140 occasions at sites throughout the U.S.A., Canada, and Europe under the auspices of the Continuing Education Department of the American Chemical Society and several other sponsors. He teaches organic chemistry and advanced synthetic organic chemistry courses for undergraduate and graduate students at Notre Dame. He has held guest professorships in Sweden and Denmark on several occasions, most recently for 15 months during 2011-2012.
Dr. Helquist has been an instructor with the American Chemical Society for 35 years.