In Person

1-D and 2-D NMR Spectroscopy: Structure Determination of Small Molecule Organic Compounds

Explore the fundamentals of sample preparation, solvent choice, pulse sequence selection, parameter optimization, data processing options, and data interpretation of one- and two-dimensional homo- and heteronuclear NMR experiments.

About the Course

Use one- and two-dimensional NMR spectroscopy to elucidate the structure of small molecule unknowns. Explore the fundamentals of sample preparation, solvent choice, pulse sequence selection, parameter optimization, data processing options, and data interpretation of one- and two-dimensional homo- and heteronuclear experiments.

Each of the NMR experiments listed in the agenda will be discussed in detail. Data interpretation will include a discussion of various NMR software (i.e., ACD, TOPSPIN, VNMR, Mnova) and analysis using plotted spectra. Data sets will be analyzed using three formats during the course: instructor led analysis, individual/small group problem sets, and independent analysis of NMR problem sets.

  • NMR Hardware Review
  • 1-D and 2-D NMR Experiment Selection
  • Homonuclear and Heteronuclear 2-D NMR Interpretation
  • NMR Structural Elucidation Strategy
  • 1-D and 2-D NMR Processing Packages

Youtube ID: Dkn0lDK9zNk


What You Will Learn

  • Minimize data analysis time
  • Optimize NMR experiment selection
  • Improve NMR data interpretation skills
  • Understand the role of NMR in structural elucidation
  • Optimize experimental NMR parameters
  • Enhance NMR vocabulary

Who Should Attend

Chemists in the pharmaceutical, consumer products, food science, forensics, or cosmetics industry who want to improve their NMR interpretation.

Course Outline

  • NMR Review

    • NMR Hardware
    • NMR Software
    • Sample Preparation
  • 1-D Experiments

    • 1H
    • 13C
    • DEPT/APT
    • Other nuclei (19F, 15N, 31P, etc.)
    • 1-D NOE
  • 2-D Experiments

    • Homonuclear
    • Heteronuclear
    • NMR Problem Solving Strategy
    • Other Experiments
    • Spectral Assignment strategy

Dates, Locations, and Prices

Five for four! Register five people for one course, one person for five courses, or any combination in between and your fifth registration is free. The free registration will be the course of the lowest price. Please note: This discount is only available if you register by fax, phone, or mail and mention this discount and it cannot be combined with any other offer.

About the Instructor(s)

Kathleen Farley

Senior Principal Scientist, Pfizer

Kathleen Farley serves as Senior Principal Scientist in the R&D division at Pfizer Inc. She has over 25 years of experience in the pharmaceutical industry.

Gregory S. Walker

Associate Research Fellow, Pfizer

Gregory S. Walker is an Associate Research Fellow at Pfizer Inc. and a recognized expert in the structural elucidation of metabolites.