Dr. Vance Jaeger is Assistant Professor in the Department of Chemical Engineering at the University of Louisville. He earned his Ph.D. in Chemical Engineering from the University of Washington and worked on several projects related to protein compatibility with ionic liquids. Later, he worked as an Alexander von Humboldt Postdoctoral Fellow at the Max Planck Institute for Biophysical Chemistry in Goettingen, Germany where he studied mutations that enhance protein crystallization. He joined the Department of Chemical Engineering faculty in 2017. Dr. Jaeger’s work has focused on molecular simulations of protein thermal stability, molecular self-assembly, amide spectroscopy, solvent-protein interactions, and the application of enhanced sampling techniques to new and interesting problems. His work has been featured in several high-impact journals including JACS, Angewandte Chemie, Biophysical Journal, and Applied Catalysis B. His current research includes projects in the areas of ionic liquids, biomineralization, membrane channel function, and protein stabilization.
Dr. Jaeger’s research group focuses on the development and application of molecular models to gain insight into the mechanism that govern thermodynamic and kinetic properties of chemical systems. These molecular models allow his group to predict and explain chemical and biological phenomena that cannot be easily studied using modern experimental techniques. Applications of his research include the tailored design of solvents for energy applications, the selection of self-assembling proteins that template nanoparticle formation, the formulation of therapeutic proteins for longer shelf-life, and the design of biomimetic membranes and membrane channels that function in extreme environments. This research is carried out in collaboration with experimental groups within the Department of Chemical Engineering and with scientists and engineers in several universities and research institutions across the world.
Dr. Jaeger currently teaches courses in Computer Applications for Chemical Engineering, Computational Chemistry and Molecular Modeling, and a Capstone Design Course which is the culmination of the Chemical Engineering undergraduate curriculum.